Laena was tall, slender, and surpassingly lovely with a great mane of silver-gold ringlets that fell down past her waist. It was said she had inherited the beauty of her mother, Princess Rhaenys Targaryen, the Queen who Never Was, and the adventurous spirit of her father, Lord Corlys Velaryon, ruling Lord of the Driftmark.
Laena was a candidate for queen during the Great Council of 101. She had one brother, Laenor, who was one year younger than her.
After the death of Queen Aemma, King Viserys I Targaryen's small council advised him to marry Laena, though she was only twelve at the time. He instead married Alicent Hightower, and House Velaryon was noticeably absent from the wedding.
Laena was engaged to a son of the Sealord of Braavos, but when his father died, he squandered his money and power and came toDriftmark. Her father repeatedly found ways to postpone their wedding, until the Braavosi exile was slain by Prince Daemon Targaryen in a duel. At 22, Laena married Daemon, and knowing that their marriage would upset the Iron Throne, they flew first to Pentos and then otherFree Cities. Their dragons, Laena's Vhagar and Daemon's Caraxes, drew crowds wherever they went. She gave birth to twin daughters,Rhaena and Baela Targaryen, in Pentos, and eventually returned to Driftmark by ship when Daemon flew to Westeros to ask for Viserys's blessing.
While at Driftmark, Laena became good friends with Princess Rhaenyra Targaryen, and they would often fly together. Rhaenyra announced the engagement of her eldest sons to Laena's daughters. Rhaenyra attended Laena during her labor of her son. The child was malformed and died an hour after being born, and Laena died three days later from childbed fever, despite the efforts of Rhaenyra's maester from Dragonstone, Gerardys. She tried to fly Vhagar one last time before she died, but collapsed on the tower steps.